For many tertiary care hospitals, the decision to withhold extracorporeal membrane oxygenation (ECMO) is becoming increasingly difficult to justify—both ethically and operationally. As clinical outcomes for ECMO continue to improve and the technology becomes more portable and accessible, the moral case for inaction grows weaker. Yet, many institutions remain sidelined, watching as patients who could have survived are transferred to distant facilities, delayed in their care, or lost entirely.
The hesitation is rarely born of apathy. Instead, it is fueled by a profound "fear of the unknown." Hospital administrators frequently see nascent ECMO programs stall, struggle to reach break-even points, or quietly fade away within their first year. These failures are rarely the result of a lack of clinical skill or dedication; rather, they stem from predictable, structural pitfalls in how these programs are built.
The Core Problem: Why Programs Falter
When hospitals attempt to build highly specialized ECMO units from the ground up without external guidance, they encounter a series of systemic failures. These issues transcend geography and institutional size. The following analysis explores the four most common failure modes and provides a roadmap for hospitals to overcome them.
1. The “Who Do You Call?” Conundrum
In a program built from scratch, everyone is a novice simultaneously. While standard intensive care unit (ICU) staff can be trained to manage ECMO circuits, they lack the "muscle memory" that only comes with years of experience. ECMO patients represent the sickest population in any hospital; when a catastrophic complication arises at 2:00 a.m., a staff of learners cannot be expected to troubleshoot with the confidence of veterans.
In established centers, there is always a “grizzled specialist”—a medical director with thousands of ECMO hours—available to consult. In a de novo program, that resource does not exist. Without this safety net, specialists often feel isolated and prone to "therapeutic abandonment," reverting to more familiar, albeit less effective, therapies. This leads to a vicious cycle: low volume leads to eroding skills, which further erodes confidence, ultimately causing the program to atrophy.
The Solution: Successful hospitals almost always leverage external partnerships. By bringing in experienced clinicians—either through strategic hiring or third-party partnerships—during the first 6–12 months, new programs gain the "lifeline" necessary to build institutional competence safely.
2. The Feast-or-Famine Staffing Trap
ECMO volume is notoriously erratic. A hospital might go six weeks without a single case, only to have three patients arrive simultaneously. This leads to the "staffing paradox" that quietly kills many programs.
- The Famine (Skill Decay): ECMO is a perishable skill. The Extracorporeal Life Support Organization (ELSO) acknowledges that gaps in bedside care have clinical consequences, often mandating retraining after extended periods of inactivity. Low volume breeds complacency and skill degradation, which leads to avoidance of the therapy.
- The Feast (The Coverage Gap): Conversely, a surge in census is equally dangerous. You cannot simply pull an RN from a general medical floor to manage an ECMO circuit. Continuous, 24/7 monitoring of a single ECMO bed requires a minimum of seven trained specialists to account for 12-hour shifts, vacations, and potential burnout. Most community hospitals lack this depth, and when they do have it, they cannot "flex up" when a second or third patient arrives.
The Solution: Hospitals must bridge gaps through robust simulation training during quiet periods. To manage the "feast" side of the equation, institutions are increasingly turning to external specialized staffing agencies that provide on-demand, high-competency ECMO clinicians who can integrate seamlessly into the team during surges.
3. Misconceptions in Revenue Cycle Management
A persistent myth in healthcare finance is that ECMO is a "money-losing" service. In reality, ECMO commands some of the highest Diagnosis-Related Group (DRG) reimbursements in modern medicine. When managed correctly, it is a financially viable and impactful service line.
The financial failure of an ECMO program is almost always a failure of the revenue cycle, not the clinical model. Most hospital billing departments are unfamiliar with the granular documentation required for ECMO. Key areas where revenue is frequently lost include:

- Coding Precision: Failure to capture the specific complexity of ECMO-related procedures.
- DRG/AP-DRG Assignment: Incorrect categorization that leads to lower reimbursement tiers.
- Physician Billing Integration: A failure to synchronize facility and professional fee billing.
The Solution: Hospitals must appoint a dedicated revenue cycle lead who understands the nuance of high-acuity billing. By working with clinicians to ensure documentation matches the intensity of the care, and by understanding outlier payments, most hospitals can achieve profitability with as few as a handful of cases per year.
4. Underestimating Administrative Infrastructure
Hospitals often focus exclusively on the clinical "hardware" (the pumps and the catheters) while neglecting the "software" (the policies, credentialing, and steering committees). An ECMO program is not just a clinical service; it is a complex administrative organism.
Without a strong framework—including standardized patient selection guidelines, clinical order sets, and quality metrics that align with ELSO standards—a program will stall. A physician champion cannot build this chassis alone. They require institutional backing and access to proven, template-driven administrative resources.
The Path Forward: A Call for Humility and Collaboration
The common thread among successful ECMO programs is an early recognition of the "institutional knowledge gap." The hospitals that thrive are those that approach the endeavor with humility. They recognize that there is no shortcut to the expertise required to manage extracorporeal life support safely.
By seeking out peer networks, utilizing external clinical experts, and aligning their revenue cycle processes from day one, hospitals can move past the initial volatility. They transition from a state of "fear of the unknown" to a state of clinical excellence.
Implications for the Future of Tertiary Care
As the standard of care evolves, the definition of a "comprehensive" tertiary care hospital will increasingly be tied to its ability to offer advanced life support. Hospitals that fail to address these four structural pillars will find themselves in a precarious position—forced to transfer their sickest patients, thereby losing revenue, reputation, and the opportunity to save lives.
The data is clear: ECMO is not just a specialty; it is a foundation of modern critical care. The hospitals that succeed are those that understand that building an ECMO program is not a solitary journey. It is a strategic undertaking that requires, above all, the willingness to learn from those who have already navigated the steep learning curve.
About the Author:
Dr. John R. Mehall is a former cardiothoracic surgeon and a nationally recognized expert in minimally invasive heart surgery, with over 4,000 operations performed and 60+ scientific articles published. He previously served as Director of Cardiothoracic Surgery for Centura Health for 10 years. His passion for expanding patient access to life-saving ECMO therapy drives his leadership as President of Integration Health.
This post appears through the MedCity Influencers program. The insights provided reflect the perspective of the author regarding business and clinical innovation in the healthcare sector.
